0102030405
Fmoc-Lys(Boc)-OH | C26H32N2O6 | CAS 71989-26-9
Property
Melting point: 130-135 °C (dec.)
Alpha: -12 º (c = 2,DMF 24 ºC)
Boiling point: 570.69°C
Density: 1.2301
Refractive index: -12 ° (C = 1, DMF)
Storage temp.: Store below +30°C.
Solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Pka: 3.88±0.21
Form: Powder
Color: White
Optical activity: [α]20/D 12±1°, c = 1% in DMF
Water Solubility: Slightly soluble in water.
Application
It is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.
Fmoc-Lys(Boc)-OH can be used for:
The solid-phase synthesis of pentasubstituted dihydroimidazolylbutyl dihydroimidazol-3-ium salts by coupling with p-methylbenzhydrylamine (MBHA) resin.
Fmoc-based peptide synthesis of bis-naphthalene diimide, a threading intercalator.
Synthesis of ε-Boc-ε-(3,5-bis-trifluoromethyl-benzyl)-α-Fmoc-L-Lysine to be used as 19F NMR based screening tool.
Package And Storage
Package:
25kg/carton drum or as your requirements.
Remark: Chemical composition and size can be optimized by the customers' requirements
Storage:
Separated from ammonium nitrate and potassium chlorate. Dry.Keep container tightly closed in a dry and well-ventilated place. Hygroscopic.
Safety Protection
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.