0102030405
DL-Serine Hydrazide Hydrochloride | D-Trp.Ome.Hcl | C12H15ClN2O2 | CAS 14907-27-8
Property
Melting point: 213-216 °C(lit.)
Density: 1.337g/cm3 at 20℃
Refractive index: -19 ° (C=5, MeOH)
Storage temp.: Keep in dark place, Sealed in dry, Room Temperature
Solubility: DMSO, (Slightly), Methanol (Slightly), Water (Slightly)
Form: Solid
Color: White to Off-White
Optical activity: [α]20/D 18°, c = 5 in methanol
Water Solubility: Soluble in water (150 mg/ml), dimethyl sulfoxide and methanol (50 mg/ml).
Application
Intermediate for the synthesis of Tryptophan derivatives.
D-Tryptophan Methyl Ester Hydrochloride is an intermediate in the synthesis of Tryptophan derivatives.
The Pictet–Spengler reaction of D-Tryptophan methyl ester hydrochloride with piperonal in various solvents has been extensively studied, the solvent-dependence of stereoselectivities could be principally attributed to the solubility difference between cis and trans products 5-HCl in the used solvent, the best stereoselectivity (cis/trans = 99:1) was obtained using nitromethane or acetonitrile as the solvent. Cialis, 12a-epi-Cialis, deuterium-labeled, 3,3,12a-d3-Cialis, and 3,3,12a-d3-12a-epi-Cialis could be efficiently synthesized from D-Tryptophan methyl ester hydrochloride.
Package And Storage
Package:
25kg/carton drum or as your requirements.
Remark: Chemical composition and size can be optimized by the customers' requirements
Storage:
Separated from ammonium nitrate and potassium chlorate. Dry.Keep container tightly closed in a dry and well-ventilated place. Hygroscopic.
Safety Protection
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.